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Cancer Metastasis and the Lymphovascular System: - Basis for Rational Therapy
von: Stanley P. L. Leong
Springer-Verlag, 2007
ISBN: 9780387692197 , 309 Seiten
Format: PDF, OL
Kopierschutz: DRM
Preis: 106,99 EUR
CONTENTS
6
CONTRIBUTORS
9
FOREWORD
13
PREFACE
15
ACKNOWLEDGMENTS
16
1. LANDMARKS AND ADVANCES IN TRANSLATIONAL LYMPHOLOGY
17
2. EMBRYONIC DEVELOPMENT OF THE LYMPHOVASCULAR SYSTEM AND TUMOR LYMPHANGIOGENESIS
33
3. LYMPHATIC ORIGIN FROM EMBRYONIC STEM CELLS
41
4. LYMPHATIC MARKERS, TUMOUR LYMPHANGIOGENESIS AND LYMPH NODE METASTASIS
54
5. ANATOMY OF THE HUMAN LYMPHATIC SYSTEM
69
6. SPECTÒCT FUSION IMAGING RADIONUCLIDE LYMPHOSCINTIGRAPHY: POTENTIAL FOR LIMB LYMPHEDEMA ASSESSMENT AND SENTINEL NODE DETECTION IN BREAST CANCER
92
7. SENTINEL NODE IDENTIFICATION USING RADIONUCLIDES IN MELANOMA AND BREAST CANCER
98
8. TARGETED INTRODUCTION OF SUBSTANCES INTO THE LYMPH NODES FOR ENDOLYMPHATIC THERAPY
114
9. MECHANISMS OF METASTASIS: SEED AND SOIL
132
10. PRECLINICAL MODELS OF REGIONAL LYMPH NODE TUMOR METASTASIS
141
11. A NEW BREAST CANCER MODEL FOR LYMPHATIC METASTASIS
169
12. LYMPH NODE MICROMETASTASES IN LUNG CANCER
178
13. EFFECTS OF CHEMOKINES ON TUMOR METASTASIS
187
14. REGIONAL LYMPH NODE METASTASES, A SINGULAR MANIFESTATION OF THE PROCESS OF CLINICAL METASTASES IN CANCER: CONTEMPORARY ANIMAL RESEARCH AND CLINICAL REPORTS SUGGEST UNIFYING CONCEPTS
195
15. PATTERNS OF METASTASIS IN HEAD AND NECK CANCER
212
16. PATTERNS OF METASTASIS IN HUMAN SOLID CANCERS
217
17. SIGNIFICANCE OF REGIONAL DRAINING LYMPH NODES IN THE DEVELOPMENT OF TUMOR IMMUNITY: IMPLICATIONS FOR CANCER IMMUNOTHERAPY
230
18. TARGETING SMALL MOLECULES IN CANCER
245
19. UPDATE ON THE ROLE OF EGFR INHIBITORS IN CANCER THERAPEUTICS
262
20. NEW PROMISES IN THE ADJUVANT, AND PALLIATIVE TREATMENT OF MELANOMA
281
21. FUTURE PERSPECTIVES AND UNANSWERED QUESTIONS ON CANCER METASTASIS AND THE LYMPHOVASCULAR SYSTEM
297
INDEX
301
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